Natural curcuminoids encapsulated in layered double hydroxides: a novel antimicrobial nanohybrid
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چکیده
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Natural curcuminoids encapsulated in layered double hydroxides: a novel antimicrobial nanohybrid
Currently, there is an increased scientific interest to discover plant based drug formulations with improved therapeutic potential. Among the cornucopia of traditional medicinal plants, Curcuma longa rhizomes have been used as a powerful antibacterial and antifungal agent. However, its practical applications are limited due to its instability under thermal and UV radiation and its low bioavaila...
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Layered double hydroxide (LDH) compounds are characterized by structures in which layers with a brucite-like structure carry a net positive charge, usually due to the partial substitution of trivalent octahedrally coordinated cations for divalent cations, giving a general layer formula [(M 1 xM 3+ x)(OH)2] . This positive charge is balanced by anions which are intercalated between the layers. I...
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This review focuses on the extensive study of different layered double hydroxides (LDHs)nanostructures and also their biological and physicochemical (in vitro) properties to encapsulateand deliver drugs with a recognized pharmacokinetic profile in a sustained/modified manner forbetter remedial efficacy contrasted to the corresponding conventional treatments using different<br ...
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The catalytic performance of Ni-Al, Mg-Al, and Co-Ni LDHs as novel nanocatalysts was evaluated in the oxidation of toluene. The samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and Fourier transform infrared spectroscopy (FTIR). The XRD and FTIR approved the structure and functional groups of the LDH, respectively. Also, the presence of cations with dif...
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A nanohybrid is assembled by ratiometrically co-loading Pt(IV) prodrugs and photosensitizers into layered double hydroxide nanoparticles. The nanohybrid shows synergistic cell-killing effects and is significantly active against the proliferation of cisplatin-resistant human cancer cells with nanomolar IC50 values. Profound mechanistic investigations confirm its action mode of combined chemo- an...
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ژورنال
عنوان ژورنال: Chemistry Central Journal
سال: 2016
ISSN: 1752-153X
DOI: 10.1186/s13065-016-0179-7